Your Firefox profile cannot be loaded, It may be missing or inaccessible
If you are not aware, Firefox, by default, stores your user data and settings in a special profile folder. The browser pulls information from this folder every time you choose to launch it. The default Firefox profile folder location is under the %APPDATA%\Mozilla\Firefox\Profiles folder. Repair the error by deleting the profiles.ini file If you are experiencing issues while accessing the Profile Manager, you can choose to create a new default Firefox profile by deleting the profiles.ini file. Do the following, Click on the Windows Start button or press the Windows key to open the Start Menu. Type %appdata% and press the ‘Enter’ key. When done, the hidden AppData\Roaming folder should become visible to you. Open the folder by double-clicking the Mozilla folder, followed by a double-click on the Firefox folder. Now, simply delete the profiles.ini file. Take care not to delete the Profiles folder, which should have a file folder icon.
It is important to mention here that the .ini file extension is identified as the file featuring a ‘Gear’ icon alongside it, something like “Configuration settings” or “Application settings.” When you start Firefox, a new profile will be created. Secondly, if you know where your profile exists, try one of the following methods to help Firefox find it. The Firefox User Profile Manager lets you create & manage Multiple User Profiles.